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Healing Process

Phases

Cell Phase

Tissue Phase

Contraction

Remolding

Components

 

 

 

 

(Section 2b. Phases of Cutaneous Wound Healing continued)

  1. Wound Contraction Phase (Begins about Day 10)

Components:
  • Fibroblast and Myofibroblast contractions
  • Movement of wound edges towards each other
  • Secretion of collagen and GAG to cement new position in place
  • Continue same process

 

Wound contraction is the process whereby open wounds close by movement of the wound edges (not just epithelium) towards the center of the wound. The mechanism of the contraction which shrinks the wound is the generation of forces in the contractile elements of the fibroblasts towards the center of the wound. With fibroblast contraction, collagen and proteoglycan is secreted essentially cementing the new tissue in place.

Impairments:

  • Malnutrition

  • Decreased perfusion
  • Corticosteriods
  • Decreased anabolism

 

Figure 11: Wound Contraction Figure 12: Wound Closure
Increased collagen and matrix deposition is shown as wound edges approach each other. Increased vascularity Wound closure by contraction.

 

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