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Section II: NORMAL BODY COMPOSITION

The body can be divided into two compartments.  Lean body mass (LBM) makes up about 75% of body weight and contains three quarters water and all the protein and mineral in the body.  The fat mass makes up about 25% of body weight and contains all the fat (water free).

Figure 1:

Legend: The contents of the lean body mass and fat mass compartments are shown.

 

Lean Body Mass

The lean body mass (LBM) contains all of the protein in the body.  The LBM is highly metabolically active and essential for survival.  Protein makes up all the muscle (50-60% of the LBM).  The critical cell structure in all organs and connective tissue, in addition to enzymes, growth factors and antibodies (Figure 1).  Any significant loss of protein is deleterious.

The LBM is maintained by an intense genetic drive for preservation and action of the anabolic hormones, growth hormone, testosterone and insulin.  Resistance exercise also maintains the anabolic activity (protein synthesis) needed to maintain LBM.  Adequate protein intake is of course required for sufficient substrate needed by the protein synthesis pathway.

 

Muscle is a very dynamic tissue, with about 50-100 grams of muscle continually broken down and re-synthesized each day.  In healthy man, the rate of loss and synthesis is equal, with a net zero nitrogen (N) balance.  With increased anabolism, (increased protein synthesis) muscle gain, is increased with a nitrogen gain.  With burn injury, there is a net loss.  Muscle is 75% water or (1 gram of muscle N=25-30 grams muscle).  Multiplying protein by 4 is a good estimate of muscle (gms).  N (grams) x 6.25 = protein (gms) x 4 = muscle (gms).  Intake of adequate calories, protein, vitamins and trace elements, are required to maintain normal body composition.

 

Fat Mass
Fat mass contains mostly fat stored as an energy reserve.  Some fats essential for survival are also present.  The fat mass typically has over 100,000 potential calories assuming the metabolic environment is in the fat burning mode as seen with pure starvation.

 

 

 

 

 

[INTRODUCTION][COMPOSITION CHANGES]

 

 

 


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