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THE   BURN   NUTRITION   MODULE

Robert H. Demling, M.D. Leslie DeSanti R.N.Dennis P. Orgill, M.D. PhD.

Section VIII

 

What are the standard clinical monitors used to assess adequacy of nutrition?

  • Assessment of energy, protein needs using Standardized Nutritional Protocols

  • Daily weights

  • Calorie intake and protein intake counts

  • Calorimetry (usually weekly)

  • Nitrogen balances when indicated

  • Net nitrogen loss should not exceed 5grams/day

The basic principles of nutritional management have been presented. However, it is essential that nutritional support be monitored and adjusted as needed to maintain goals and minimize complications.

Standard monitors must be in place. Of extreme importance in managing burns is that nutritional protocols, as standards of care, must be present. Metabolism and Nutrition are key components of body function and require a well designed program of management.

This program includes the monitoring of energy and protein needs. Daily weights, calorie and protein intakes, indirect calorimetry weekly as well as nitrogen balance measures especially if there is evidence of excessive weight loss or symptoms of excess lean mass loss. 

 

What are the standard laboratory tests used to monitor nutrition?

  • Electrolytes including potassium, magnesium and phosphate (major shifts occur post burn)
  • Blood urea nitrogen, creatinine (a marker of catabolism relative to renal function)
  • Blood glucose (hyperglycemia - a common problem)
  • Liver profile (monitoring CHOLESTASIS)
  • Triglycerides (monitoring adequacy of fat clearance; adjust fat intake)
  • Prealbumin and Transferrin, a marker of anabolism and catabolism


Because of the major metabolic changes post burn and further alterations with nutrition, standard laboratory tests are needed to maintain homeostasis and detect complications. 

Major electrolyte shifts occur with burn injury and nutrition. The intracellular electrolytes, magnesium and phosphate level characteristically decrease to very low levels with onset of nutrition as cell mass increases. Increased provision of key electrolytes is needed to avoid major complications. Hypernatremia can indicate inadequate hydration. Blood urea nitrogen typically increases with protein breakdown but the level must be assessed relative to creatinine (renal function). An elevated BURN is also a marker of inadequate hydration.

Blood glucose is a key monitor since hyperglycemia is a characteristic of burn injury. Glucose intake and insulin use must be carefully adjusted. 

Liver function abnormalities are common especially increasing alkaline phosphates. A rapidly rising level may indicate excess fat deposition (which often means overfeeding).

Serum triglycerides measure adequacy of fat clearance and should not exceed 250mg/dl. If elevated, fat intake should be decreased. Prealbumin and Transferrin are markers of protein synthesis and degradation. A continually decreasing value usually reflects inadequate protein intake.

 

What clinical changes should initiate a nutrition adjustment?

  1. An excessive and progressive weight loss (need to increase calories and micronutrients)

  2. Evidence of an excessive lean mass loss e.g.. weakness, poor healing of wounds, grafts, donors (assess nitrogen balance, likely increase protein and micronutrients)

  3. Evidence of excess CO2 production reflecting excess carbohydrates (adjust CHO intake)

 

Evidence of inadequate energy intake would be a progressive weight loss exceeding that predicted by the degree of injury. A reassessment of calorie needs should be done with a likely increase in both calories and micronutrients.

Also progressive weakness, unexpected poor healing of the wound, grafts and donor sites would indicate the need for increased protein (check nitrogen balance). Check also for specific micronutrient deficiencies.

Finally, an excessive CO2 production would indicate excessive carbohydrate intake which needs to be adjusted. Measuring a respiratory quotient would make the diagnosis. An RQ exceeding 1.0 is an indicator of excessive carbohydrates.


 

 


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