Despite the fact that itching, especially burn related itch, is one of the most serious problems a burn survivor can have, very little is known about the mechanism. This lack of knowledge is the result of one, a lack of research on the mechanism, and two, the complex nature of the injured skin and the nerves of the skin.^1-10

There isn't even a good definition of itch. The best one is "a sensation that leads to a desire to scratch. It is the predominant symptom of any inflammatory skin disorder and a healed burn is just that.

The lack of information can be inferred from the fact that no specific anti-itch drug has been available, although a promising new approach has arrived.^11-13