|
VII. CLINICAL EXPERIENCE WITH 5% DOXEPIN CREAM
(PRUDOXIN)
The extremely potent antihistamine
properties of the Doxepin compound, placed in a topical cream
delivery system, is an ideal approach to management of burn
wound itch.
The 5% Doxepin cream (Prudoxin:
HealthPoint) has been used effectively and safely for
management of itch in a host of dermatological disorders and
is the treatment of choice even over the use of topical
corticosteroids, the latter would not be advantageous for a
healing burn. The cream, when applied, is rapidly absorbed
into the wound such that within 10 minutes a moisturizer can
be applied.
|
ADVANTAGES
OF DOXEPIN CREAM |
- rapidly
absorbed into itchy wound
- rapid
onset of anti-itch activity
- rapidly
decreases wound erythema
- acts
for 6-8 hours
- no
tachyphylaxis develops
- approved
product for itching
- can
apply moisturizer after Doxepin is absorbed onto
wound
|
| CASE
STUDIES |
|
Use
of topical Prudoxin
(5%
Doxepin Cream)
to
treat itching and erythema in the healed burn wound |
| Pre
and Post Measurements Made |
|
Itch
Scale 0-10
Erythema
Scale
|
(10
being worst)
0-normal
color
1-pink
2-red
3-red
to purple |
|
