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MOIST
HEALING AND WOUND CARE INCLUDING BURNS
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(Advantages
and Current Approaches)
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Section
IV. MOIST WOUND HEALING FOR THE BURN WOUND?
Continued . . .
C
) Other Antibiotic Solutions for Burn
1)
Neomycin Sulfate
is bacteriocidal in action being effective against gram
negative organisms but not effective against Pseudomonas. It
has not been found to penetrate devitalized tissue and is
therefore used on clean wound surfaces to control bacterial
growth. The usual concentration for topical use is 0.1 to
0.2%.
Characteristics
of 0.1% Neomycin Solution
2)
Polymyxin B Sulfate occurs
as a powder which readily dissolves in solution. Polymyxin B
is bacteriocidal for most gram negative species but has no
gram positive organism or fungal activity. It is non-toxic to
tissues and skin sensitivity is rare.
3
) Bacitracin
Bacitracin is a
polypeptide bacteriostatic antibiotic active against many gram
positive organisms, but not against gram negative organisms or
fungi. Bacitracin is precipitated from solution by any heavy
metals. It does not penetrate tissue and is not toxic when
applied topically. Skin sensitivity is rare.
Often combinations of
bacitracin and neomycin are used to increase antibacterial
Properties. Nystatin an anti-fungal can also be added.
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